Mutliple studies have shown how the skin microbiome of people with eczema is depleted compared to healthy subjects.
One paper shows how the skin is even more damaged during flare-ups
"[Patients with Eczema] often have increased Staphylococcus aureus on their skin,”
"[The eczema skin environment] kills off beneficial microbes from the skin and permits the bad bacteria to overgrow,
"[The eczema skin environment] kills off beneficial microbes from the skin and permits the bad bacteria to overgrow,
The above article noted that “dysregulation of the skin microbiome is more pronounced in people with severe symptoms”.
It is also thought that toxins are released by the microbes on eczema skin that make the rash worse.